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Year : 2011  |  Volume : 12  |  Issue : 1  |  Page : 31-33

Intramuscular ketamine in acute depression: A case report

Professor of psychiatry, Narayana medical college, Nellore. AP, India

Correspondence Address:
C Harihar
Professor of psychiatry, Department of psychiatry, Narayana medical college, Chintareddy Palem, Nellore-524002. AP.
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Source of Support: None, Conflict of Interest: None

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In the pharmacological management of depression, antidepressant drugs take about two weeks for the onset of their therapeutic action while electroconvulsive therapy though faster, is a cumbersome procedure requiring an anesthetist and many gadgets. Recent studies have shown that ketamine when given to severely depressed patients in the dose of 0.5mg/kg body weight as a slow intravenous infusion over 40 minutes brought about rapid and significant relief within a few hours to within a day. It was however a transitor y improvement which lasted for up to a week. As the dose of ketamine administered was very small, it was now tried in the intramuscular route with similar rapid improvement of depressive symptoms in a 25 year old man. His case is reported here as it promises to be an easy tool for providing quick relief to severely depressed patients.

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