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Impact of traumatic brain injury on cognitive functions
Padilla-Zambrano Huber Said1, Amrita Ghosh2, Ranabir Pal3, Nataraja Poli4, Luis Rafael Moscote-Salazar5, Amit Agrawal6
1 MD, Centro De Investigaciones Biomédicas, Cartagena Neurotrauma Research Group Research, Faculty of Medicine, University of Cartagena, Cartagena De Indias, Bogota, Colombia
2 MD (Biochemistry), MSc. (Medical Biochemistry): Faculty, Department of Biochemistry, Medical College, Kolkata, West Bengal, India
3 MD, PhD: Professor and Chair (Head), Department of Community Medicine, MGM Medical College and LSK Hospital, Kishanganj, Bihar, India
4 Assistant Professor, Department of Neurology, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, India
5 Neurosurgery-Critical Care, RED LATINO Organización Latinoamericana De Trauma Y Cuidado Neurointensivo, Bogota, Colombia
6 Professor, Department of Neurosurgery, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, India
Correspondence Address:
Dr. Amit Agrawal
Department of Neurosurgery, Narayana Medical College and Hospital, Nellore, 524 003, Andhra Pradesh
India
 Source of Support: None, Conflict of Interest: None  | 3 |
DOI: 10.4103/AMH.AMH_14_18
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In this systematic review, we summarize the current understanding and controversies on cognitive sequelae after traumatic brain injury (TBI) to understand the cognitive deficits such as memory, attention, executive functions, and unawareness of their deficits in TBI patients. This review presents the cognitive sequel of patients with moderate-to-severe TBI by a comprehensive focused conglomeration of research publications by searching various resources. A search strategy with specific inclusion criteria was performed in PubMed, Cochrane, Web of Science, and the WHO Global Health Library. This review noted that TBI is related with increase of various neurological and non-neurological disorders including problems with attention, inability to concentrate, speech and language dysfunctions, learning and memory impairment, impaired reasoning, impaired planning and problem-solving. This review found that patients' cognitive deficits are common in victims of moderate to severe TBI often as the long-lasting sequalae. The present review suggests that there is a need for further research to develop unique rehabilitation methods that will help to enhance brain plasticity and process of recovery after TBI.
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